Sessions
Development in Allogeneic Cellular Therapies
What are the Cell and Gene Therapies of the Future?
Development in Neurology and Ophthalmology
Development in Stem Cell Therapeutics and Regenerative Medicine
Development in Cell & Gene Therapy to Treat Rare and Difficult Indications
Development in Cell Therapy for Solid Tumours
Development for Non-Oncology Indications
Development in Allogeneic Cellular Therapies
11:00 Chairperson’s Opening
Dominic Clarke, Chief Technical Officer, DLS
11:05 A New Approach to Treating Cancer – miCAR Cellular Engineering (Live-Stream)
- Allo constructs for cell based therapies in cancer are evolving to deliver, safety, efficacy and persistence
- We will describe the utilisation of Antion’s miCAR platform to engineer the most efficient cells
Sven Kili, Chief Executive Officer, Antion Biosciences SA
11:20 Effective Donor Sourcing Strategies to Enhance Downstream Efficiency and Scalability of Allogeneic Cell Therapies
- Examining the impact of inter-donor variability of cellular source material
- How streamlined donor management can improve outcomes utilizing inherently variable starting material for manufacture of off-the-shelf therapies
- Benchmarking how raw material supply partners can help mitigate risk and provide sustainable growth strategies to overcome supply chain hurdles – a case study
Kimberly Negrin, Director, Cell Therapy Strategy and Business Operations, Charles River Laboratories
11:35 Tackling Antigen Escape & Manufacturing Cost for Cell Therapies
- Will review novel BAFF Ligand CAR with 3 antigens on a single CAR
- Will review dynamic Antigen programming approach
- Will review allogenic approaches to Cell Therapies
Jeff Liter, Chief Executive Officer, Luminary Therapeutics
11:50 Cell Therapy Media: A New Paradigm
- Cell Therapy Media directly impacts therapeutic potency
- Historically limited options for creating Media optimized to your ecosystem and CQA’s
- We present a novel paradigm for owning, configuring and ordering your media from bench to bioreactor
David Sheehan, Founder, President and Chief Executive Officer, Nucleus Biologics
12:05 Speaker Q&A and Panel Discussion