Supply, Demand and Technical Challenges for Plasmid-Mediated Gene Therapy

19 Jan 2023
15:30
Supply Chain and Technical Operations Track
SPONSORED BY
Aldevron
Polyplus

11:00am Chair Introduction

Michael Lawlor, Professor, Medical College of Wisconsin

 

11:05am Presentation: TBA

Fred Chereau, Chief Executive Officer, LogicBio Therapeutics

 

11:20am Presentation: TBA

Emma Bjorgum, Vice President, Client Services, DNA, Aldevron

 

11:35am Presentation: TBA

Senior Representative, Ray Therapeutics

 

11:50am Presentation: Designing Quality and Scalability Into Upstream Processes for Successful AAV manufacturing

  • Improving AAV yield and quality by focusing on key step of upstream process: optimizing scalability of transient transfection step
  • Engineering optimized AAV plasmids to improve both infectivity and quality of viral particles
  • Developing  a robust and GMP compliant, yet cost-effective AAV manufacturing process to reduce cost per dose

Roel Gordijn, Chief Commercial Officer, Polyplus

 

12:05pm Closing Panel with Q&A

With all session participants

Speakers

Emma Bjorgum
Vice President, Client Services, DNA
Aldevron
Fred Chereau
Founder and Chief Executive Officer
LogicBio Therapeutics
Michael Lawlor
Professor
Medical College of Wisconsin
Roel Gordijn
Chief Commercial Officer
Polyplus